NEURAL REGENERATION RESEARCH
Vol 18｜No. 2｜February 2023
Functions and mechanisms of cytosolic phospholipase A2 in central nervous system trauma
胞浆型磷脂酶A2在中枢神经系统创伤中的功能和机制
Hao-Jie Zhang, Yi-Tuo Chen, Xin-Li Hu, Wan-Ta Cai, Xiang-Yang Wang, Wen-Fei Ni, Kai-Liang Zhou
The mechanism and relevant mediators associated with neuronal apoptosis and potential therapeutic targets in subarachnoid hemorrhage
蛛网膜下腔出血后神经细胞凋亡的机制、介质及潜在的治疗靶点
Qi Tian, Sheng Liu, Shou-Meng Han, Wei Zhang, Xian-Yao Qin, Jun-Hui Chen, Cheng-Li Liu, Yu-Jia Guo, Ming-Chang Li
Simulating traumatic brain injury in vitro: developing high throughput models to test biomaterial based therapies
体外模拟创伤性脑损伤：开发高通量模型以测试基于生物材料的疗法
Raja Haseeb Basit, Jessica Wiseman, Farhana Chowdhury, Divya Maitreyi Chari
Brain and spinal cord trauma: what we know about the therapeutic potential of insulin growth factor 1 gene therapy
脑和脊髓创伤：我们对胰岛素生长因子 1 基因治疗的治疗潜力的了解
María Jose Bellini, Florencia Labombarda
The potential of gene therapies for spinal cord injury repair: a systematic review and meta-analysis of pre-clinical studies
脊髓损伤修复中基因疗法的潜力：临床前研究的系统评价和荟萃分析
Catriona J. Cunningham, Mindaugas Viskontas, Krzysztof Janowicz, Yasmin Sani, Malin E. Håkansson, Anastasia Heidari, Wenlong Huang, Xuenong Bo
Microglia depletion as a therapeutic strategy: friend or foe in multiple sclerosis models?
小胶质细胞耗竭作为一种治疗策略：多发性硬化模型中的朋友还是敌人？
Victoria Sofia Berenice Wies Mancini, Anabella Ayelen Di Pietro, Laura Andrea Pasquini
Safety, immunogenicity, efficacy, and acceptability of COVID-19 vaccination in people with multiple sclerosis: a narrative review
COVID-19 疫苗在多发性硬化患者中的安全性、免疫原性、有效性和可接受性：叙述性文献综述
Fioravante Capone, Mariagrazia Rossi, Alessandro Cruciani, Francesco Motolese, Fabio Pilato, Vincenzo Di Lazzaro
c-Abl kinase at the crossroads of healthy synaptic remodeling and synaptic dysfunction in neurodegenerative diseases
c-Abl 激酶处于神经退行性疾病中健康突触重塑和突触功能障碍的十字路口
Daniela A. Gutiérrez, América Chandía-Cristi, María José Yáñez, Silvana Zanlungo, Alejandra R. Álvarez
Mortalin/Hspa9 involvement and therapeutic perspective in Parkinson’s disease
Mortalin/Hspa9 在帕金森病中的参与和治疗前景
Baptiste Texier, Morgane Prime, Djamaa Atamena, Pascale Belenguer, Marion Szelechowski
Cre-recombinase systems for induction of neuron-specific knockout models: a guide for biomedical researchers
用于诱导神经元特异性敲除模型的 Cre 重组酶系统：生物医学研究人员的向导
Tetiana Shcholok, Eftekhar Eftekharpour
Prenatal programing of motivated behaviors: can innate immunity prime behavior?
动机行为的产前编程：先天免疫能引发行为吗？
Larisa Montalvo-Martínez, Gabriela Cruz-Carrillo, Roger Maldonado-Ruiz, Luis A. Trujillo-Villarreal, Eduardo A. Garza-Villarreal, Alberto Camacho-Morale
Approaches to quantify axonal morphology for the analysis of axonal degeneration
量化轴突形态以分析轴突变性的方法
Alex Palumbo, Marietta Zille
Advances in quantitative analysis of astrocytes using machine learning
利用机器学习对星形胶质细胞进行定量分析的进展
Demetrio Labate, Cihan Kayasandik
The role of mitochondria in the recovery of neurons after injury
线粒体在损伤后的神经元恢复中的作用
Taylor McElroy, Rola S. Zeidan, Laxmi Rathor, Sung Min Han, Rui Xiao
Kainate receptors in the CA2 region of the hippocampus
海马 CA2 区的红藻氨酸受体
Yuniesky Andrade-Talavera, Antonio Rodríguez-Moreno
(Phospho)creatine: the reserve and merry-go-round of brain energetics
(磷酸）肌酸：大脑能量的储备和快乐的轮回
Hong-Ru Chen, Ton DeGrauw, Chia-Yi Kuan
Understanding the timing of brain injury in fetal growth restriction: lessons from a model of spontaneous growth restriction in piglets
了解胎儿生长受限导致脑损伤的时机：来自仔猪自发生长受限模型的经验教训
Hannah Musco, Julie A. Wixey
MicroRNA-based targeting of the Rho/ROCK pathway in therapeutic strategies after spinal cord injury
脊髓损伤后治疗策略中基于 MicroRNA 的 Rho/ROCK 通路靶向
Tetsu Kimura, Yuta Horikoshi
A perspective on causality assessment in epigenetic research on neurodegenerative disorders
神经退行性疾病表观遗传学研究中因果关系评估的观点
Philippos Koulousakis, Assia Tiane, Niels Hellings, Jos Prickaerts, Daniel van den Hove, Tim Vanmierlo
Synaptopathy in CHMP2B frontotemporal dementia highlights the synaptic vesicle cycle as a therapeutic target
CHMP2B 额颞叶痴呆的突触病变突出突触小泡周期作为治疗靶点
Miranda Robbins, Emma L. Clayton
Microtubule affinity regulating kinase (MARK/Par1) isoforms differentially regulate Alzheimer’s disease-like TAU missorting and Aβ-mediated mediated synapse pathology
微管亲和调节激酶 (MARK/Par1) 亚型差异调节阿尔茨海默病样 TAU 错配和 Aβ 介导的突触病理学
Jana Chudobová, Hans Zempel
Turning up the NAD+-mitophagy axis to treat Alzheimer’s disease
调高 NAD+-mitophagy 轴以治疗阿尔茨海默病
Evandro F. Fang, Alexander Anisimov
Acid-sensing ion channel 1a: a novel target in Alzheimer’s disease?
酸感应离子通道 1a：阿尔茨海默病的新靶点？
Dalila Mango, Robert Nisticò
The Wnt/β-catenin signaling: a multifunctional target for neuroprotective and regenerative strategies in Parkinson’s disease
Wnt/β-连环蛋白信号：帕金森病神经保护和再生策略的多功能靶点
Annalucia Serafino, Mauro Cozzolino
Apoptotic retinal ganglion cell loss is accompanied by complement and cytokine response in the βB1-CTGF primary open-angle glaucoma mouse model
在βB1-CTGF原发性开角型青光眼小鼠模型中，凋亡性视网膜神经节细胞丢失伴随着补体和细胞因子反应
Ana Maria Mueller-Buehl, Sabrina Reinehr
Schwann cell extracellular vesicles: judging a book by its cover
许旺细胞胞外囊泡：从封面判断一本书
Steven L. Gonias, Wendy M. Campana
Perspective on inflammatory cytokines in open spinal dysraphism
开放性脊柱裂中炎性细胞因子的观点
Friederike Knerlich-Lukoschus
On the interaction of a donepezil huprine hybrid with synthetic membrane models
多奈哌齐石杉碱杂种与合成膜模型的相互作用
Pablo Zambrano
Commentary on “PANoptosis-like cell death kills retinal neurons following OGD/R and aHIOP injury”
Macarena S. Arrázola, Felipe A. Court
Potential role of PANoptosis in neuronal cell death: comment on ‘PANoptosis-like cell death kills retinal neurons following OGD/R and aHIOP injury’
Yanyan Sun, Changlian Zhu
PANoptosis: new insights in regulated cell death in ischemia/reperfusion models
PANoptosis：缺血/再灌注模型中调节细胞死亡的新见解
Paloma González-Rodríguez, Arsenio Fernández-López
脑损伤与神经再生
Neural stem cell-derived exosome as a nano-sized carrier for BDNF delivery to a rat model of ischemic stroke
神经干细胞源性外泌体作为纳米级载体向缺血性脑卒中模型递送脑源性神经营养因子
Zhi-Han Zhu, Feng Jia, Waqas Ahmed, Gui-Long Zhang, Hong Wang, Chao-Qun Lin, Wang-Hao Chen, Lu-Kui Chen
Modified constraint-induced movement therapy enhances cortical plasticity in a rat model of traumatic brain injury: a resting-state functional MRI study
改良的约束诱导运动疗法干预可脑创伤大鼠的大脑皮质可塑性
Cheng-Cheng Sun, Yu-Wen Zhang, Xiang-Xin Xing, Qi Yang, Ling-Yun Cao, Yu-Feng Cheng, Jing-Wang Zhao, Shao-Ting Zhou, Dan-Dan Cheng, Ye Zhang, Xu-Yun Hua, He Wang, Dong-Sheng Xu
Knockout of Sirt2 alleviates traumatic brain injury in mice
敲除沉默信息调节因子2基因可减轻创伤性脑损伤
Wei Wang, Qiu-Yuan Gong, Lin Cai, Yao Jing, Dian-Xu Yang, Fang Yuan, Hao Chen, Heng-Li Tian
Repetitive transcranial magnetic stimulation promotes neurological functional recovery in rats with traumatic brain injury by upregulating synaptic plasticity-related proteins
Fang-Fang Qian, You-Hua He, Xiao-Hui Du, Hua-Xiang Lu, Ren-Hong He, Jian-Zhong Fan
Treatment of radiation-induced brain injury with bisdemethoxycurcumin
双去甲氧基姜黄素可治疗辐射性脑损伤
Yun-Qian Chang, Gui-Juan Zhou, Hong-Mei Wen, Duan-Qun He, Chen-Lin Xu, Ya-Rui Chen, Yi-Hui Li, Shuang-Xi Chen, Zi-Jian Xiao, Ming Xie
A novel aged mouse model of recurrent intracerebral hemorrhage in the bilateral striatum
一种新型双侧纹状体复发性脑出血的老年小鼠模型
Li-Min Wang, Zhi-Hua Liu, Hong-Lei Ren, Xue-Mei Chen, Jun-Min Wang, Hui-Min Cai, Li-Ping Wei, Hui-Hong Tian, Jian Wang, Li-Juan Wang
β-Estradiol 17-acetate enhances the in vitro vitality of endothelial cells isolated from the brain of patients subjected to neurosurgery
β-雌二醇17-乙酸酯可提高神经外科患者大脑内皮细胞的活力
Sonia Guzzo, Pasquale De Bonis, Barbara Pavan, Luciano Fadiga
脊髓损伤与神经再生
Knockdown of polypyrimidine tract binding protein facilitates motor function recovery after spinal cord injury
敲低多嘧啶束结合蛋白可促进脊髓损伤后运动功能的恢复
Ri-Yun Yang, Rui Chai, Jing-Ying Pan, Jing-Yin Bao, Pan-Hui Xia, Yan-Kai Wang, Ying Chen, Yi Li, Jian Wu, Gang Chen
Nicotinic acetylcholine signaling is required for motor learning but not for rehabilitation from spinal cord injury
烟碱乙酰胆碱有助于脊髓损伤后运动恢复但非康复训练促进运动功能恢复所必需
Yue Li, Edmund R. Hollis II
Identification of injury type using somatosensory and motor evoked potentials in a rat spinal cord injury model
体感和运动诱发电位联合监测识别手术致机械性原发性脊髓损伤的类型
Rong Li, Han-Lei Li, Hong-Yan Cui, Yong-Can Huang, Yong Hu
Effects of C2 hemisection on respiratory and cardiovascular functions in rats
C2脊髓半切对大鼠呼吸和心血管功能的影响
Pauline Michel-Flutot, Arnaud Mansart, Abdallah Fayssoil, Stéphane Vinit
神经退行性疾病与神经再生
The Alzheimer’s disease-associated gene TREML2 modulates inflammation by regulating microglia polarization and NLRP3 inflammasome activation
阿尔茨海默病治疗的新标靶：TREML2通过调节小胶质细胞极化和 NLRP3 炎性体激活来调节炎症
Si-Yu Wang, Xin-Xin Fu, Rui Duan, Bin Wei, Hai-Ming Cao, Yan E, Shuai-Yu Chen, Ying-Dong Zhang, Teng Jiang
周围神经损伤与神经再生
Functional recovery and muscle atrophy in pre-clinical models of peripheral nerve transection and gap-grafting in mice: effects of 4-aminopyridine
周围神经横断和缺损移植的临床前小鼠模型的功能恢复和肌肉萎缩：4-氨基吡啶的作用
Jung Il Lee, M A Hassan Talukder, Zara Karuman, Anagha A. Gurjar, Prem Kumar Govindappa, Jagadeeshaprasad M. Guddadarangaiah, Kristen M. Manto, Grant D. Wandling, John P. Hegarty, David L. Waning, John C. Elfar
Platelet-rich plasma promotes peripheral nerve regeneration after sciatic nerve injury
富血小板血浆可有效促进损伤坐骨神经后周围神经的再生
Su-Long Wang, Xi-Lin Liu, Zhi-Chen Kang, Yue-Shu Wang
视神经损伤与神经再生
PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons
缺血再灌注损伤视网膜神经元泛死亡样细胞死亡
Wei-Tao Yan, Wen-Juan Zhao, Xi-Min Hu, Xiao-Xia Ban, Wen-Ya Ning, Hao Wan, Qi Zhang, Kun Xiong
Neuroprotective effects of exogenous brain-derived neurotrophic factor on amyloid-beta 1–40-induced retinal degeneration
外源性脑源性神经营养因子对淀粉样β蛋白1-40致视网膜变性的神经保护
Mohd Aizuddin Mohd Lazaldin, Igor Iezhitsa, Renu Agarwal, Puneet Agarwal, Nafeeza Mohd Ismail
Sox11b regulates the migration and fate determination of Müller glia-derived progenitors during retina regeneration in zebrafish
Sox11b可调节斑马鱼视网膜再生过程中 Müller 胶质祖细胞的迁移和命运
Kaida Song, Zihao Lin, Lining Cao, Bowen Lu, Yuxi Chen, Shuqiang Zhang, Jianfeng Lu, Hui Xu
Anti-inflammatory effect of miR-125a-5p on experimental optic neuritis by promoting the differentiation of Treg cells
miR-125a-5p促进调节性T细胞分化对视神经炎的抗炎效应
Jia-Lin Zhan, Yan-Ling Huang, Qiao-Wen Liang, Xiao-Sheng Qu, Zi-Mei Dong, Yi Du, Wen-Jing Luo
疼痛与神经再生
Intrathecal liproxstatin-1 delivery inhibits ferroptosis and attenuates mechanical and thermal hypersensitivities in rats with complete Freund’s adjuvant-induced inflammatory pain
鞘内注射利普司他汀1抑制铁死亡并减轻炎性疼痛
Yi-Fan Deng, Ping Xiang, Jing-Yi Du, Jian-Fen Liang, Xiang Li
Emerging evidence of neuronal cellstargeting SARS-CoV-2 causing anosmia associated with COVID-19